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Contradictory role of CD97 in basal and tumor necrosis factor α-induced osteoclastogenesis in vivo

OBJECTIVE: CD97, a member of the EGF-TM7 family of adhesion GPCR, is expressed on various cell types. We report here the contradictory role of CD97 in osteoclastogenesis in both basal and response to TNF treatment. We found that RANKL induced CD97 in FACS sorted osteoclast precursor cells. To elucid...

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Vydáno v:Arthritis Rheumatol
Hlavní autoři: Won, Hee Yeon, Mun, Se Hwan, Shin, Bongjin, Lee, Sun-Kyeong
Médium: Artigo
Jazyk:Inglês
Vydáno: 2016
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514326/
https://ncbi.nlm.nih.gov/pubmed/26663852
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.39538
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