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Pigment epithelium-derived factor protects retinal ganglion cells from hypoxia-induced apoptosis by preventing mitochondrial dysfunction

AIM: To investigate the potential of pigment epithelium-derived factor (PEDF) to protect the immortalized rat retinal ganglion cells-5 (RGC-5) exposed to CoCl(2)-induced chemical hypoxia. METHODS: After being differentiated with staurosporine (SS), RGC-5 cells were cultured in four conditions: contr...

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Detalhes bibliográficos
Publicado no:Int J Ophthalmol
Main Authors: Tian, Shu-Wei, Ren, Yuan, Pei, Jin-Zhi, Ren, Bai-Chao, He, Yuan
Formato: Artigo
Idioma:Inglês
Publicado em: International Journal of Ophthalmology Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514264/
https://ncbi.nlm.nih.gov/pubmed/28730105
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18240/ijo.2017.07.05
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