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Insulin upregulates betatrophin expression via PI3K/Akt pathway

Betatrophin is regarded as a liver-produced hormone induced by insulin resistance (IR). However, it remains largely unknown how IR regulates betatrophin expression. To study whether IR could regulate betatrophin expression and the corresponding molecular mechanisms, betatrophin levels were examined...

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Detalles Bibliográficos
Publicado en:Sci Rep
Main Authors: Lu, Puhan, Chen, Xi, Zhang, Zeqing, Zhang, Jianhua, Yang, Yan, Liu, Zhelong, Xie, Junhui, Shao, Shiying, Zhou, Xinrong, Hu, Shuhong, He, Wentao, Zhao, Jiajun, Yu, Xuefeng
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514142/
https://ncbi.nlm.nih.gov/pubmed/28717133
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06052-y
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