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Prostacyclin reverses platelet stress fibre formation causing platelet aggregate instability

Prostacyclin (PGI(2)) modulates platelet activation to regulate haemostasis. Evidence has emerged to suggest that thrombi are dynamic structures with distinct areas of differing platelet activation. It was hypothesised that PGI(2) could reverse platelet spreading by actin cytoskeletal modulation, le...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Yusuf, M. Z., Raslan, Z., Atkinson, L., Aburima, A., Thomas, S. G., Naseem, K. M., Calaminus, S. D. J.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514131/
https://ncbi.nlm.nih.gov/pubmed/28717253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05817-9
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