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Prostacyclin reverses platelet stress fibre formation causing platelet aggregate instability

Prostacyclin (PGI(2)) modulates platelet activation to regulate haemostasis. Evidence has emerged to suggest that thrombi are dynamic structures with distinct areas of differing platelet activation. It was hypothesised that PGI(2) could reverse platelet spreading by actin cytoskeletal modulation, le...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Sci Rep
Hauptverfasser: Yusuf, M. Z., Raslan, Z., Atkinson, L., Aburima, A., Thomas, S. G., Naseem, K. M., Calaminus, S. D. J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514131/
https://ncbi.nlm.nih.gov/pubmed/28717253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05817-9
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