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Protein-protein binding selectivity and network topology constrain global and local properties of interface binding networks

Protein-protein interactions networks (PPINs) are known to share a highly conserved structure across all organisms. What is poorly understood, however, is the structure of the child interface interaction networks (IINs), which map the binding sites proteins use for each interaction. In this study we...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Holland, David O., Shapiro, Benjamin H., Xue, Pei, Johnson, Margaret E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514078/
https://ncbi.nlm.nih.gov/pubmed/28717235
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05686-2
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