Common variants of T-cells contribute differently to phenotypic variation in sarcoidosis

The involvement of the immune system, particularly the role of T-cells, in sarcoidosis is unclear. The existence of higher CD4+ T-cells and increased CD4/CD8 ratio may indicate a pathogenic role of T-cells in the disease. In this study, we quantified the contribution of T-cells associated variants a...

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Publicado no:Sci Rep
Main Authors: Rivera, Natalia V., Hagemann-Jensen, Michael, Ferreira, Manuel A. R., Kullberg, Susanna, Eklund, Anders, Martin, Nicholas G., Padyukov, Leonid, Grunewald, Johan
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5514043/
https://ncbi.nlm.nih.gov/pubmed/28717140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05754-7
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