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Stimulation of autophagy prevents intestinal mucosal inflammation and ameliorates murine colitis

BACKGROUND AND PURPOSE: Defective autophagy contributes to the pathogenesis of inflammatory disorders such as inflammatory bowel disease and there are interactions between autophagy and inflammation. Here we have analysed the effects of autophagy stimulators on murine colitis. EXPERIMENTAL APPROACH:...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Macias‐Ceja, Dulce C, Cosín‐Roger, Jesús, Ortiz‐Masiá, Dolores, Salvador, Pedro, Hernández, Carlos, Esplugues, Juan V, Calatayud, Sara, Barrachina, María D
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513861/
https://ncbi.nlm.nih.gov/pubmed/28500644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13860
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