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Clinical utility of evolocumab in the management of hyperlipidemia: patient selection and follow-up

Inhibition of PCSK9 is a novel therapeutic strategy aimed at reducing low-density-lipoprotein cholesterol (LDL-C) and cardiovascular risk. Evolocumab is a fully humanized monoclonal antibody that inhibits PCSK9, an enzyme that binds to LDL receptors and prevents them from recycling to the hepatocyte...

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Detalhes bibliográficos
Publicado no:Drug Des Devel Ther
Main Authors: Dixon, Dave L, Buckley, Leo F, Trankle, Cory R, Kadariya, Dinesh, Abbate, Antonio
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513834/
https://ncbi.nlm.nih.gov/pubmed/28744103
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S114091
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