A Novel Single-Cell FISH-Flow Assay Identifies Effector Memory CD4(+) T cells as a Major Niche for HIV-1 Transcription in HIV-Infected Patients

Cells that actively transcribe HIV-1 have been defined as the “active viral reservoir” in HIV-infected individuals. However, important technical limitations have precluded the characterization of this specific viral reservoir during both treated and untreated HIV-1 infections. Here, we used a novel...

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Publicado no:mBio
Main Authors: Grau-Expósito, Judith, Serra-Peinado, Carla, Miguel, Lucia, Navarro, Jordi, Curran, Adrià, Burgos, Joaquin, Ocaña, Imma, Ribera, Esteban, Torrella, Ariadna, Planas, Bibiana, Badía, Rosa, Castellví, Josep, Falcó, Vicenç, Crespo, Manuel, Buzon, Maria J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513707/
https://ncbi.nlm.nih.gov/pubmed/28698276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/mBio.00876-17
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