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Counselling framework for moderate-penetrance cancer-susceptibility mutations

The use of multigene panels for the assessment of cancer susceptibility is expanding rapidly in clinical practice, particularly in the USA, despite concerns regarding the uncertain clinical validity for some gene variants and the uncertain clinical utility of most multigene panels. So-called ‘modera...

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Detalhes bibliográficos
Publicado no:Nat Rev Clin Oncol
Main Authors: Tung, Nadine, Domchek, Susan M., Stadler, Zsofia, Nathanson, Katherine L., Couch, Fergus, Garber, Judy E., Offit, Kenneth, Robson, Mark E.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513673/
https://ncbi.nlm.nih.gov/pubmed/27296296
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrclinonc.2016.90
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