Potassium citrate prevents increased osteoclastogenesis resulting from acidic conditions: Implication for the treatment of postmenopausal bone loss

The extracellular acidic milieu in bones results in activation of osteoclasts (OC) and inhibition of osteoblasts (OB) causing a net loss of calcium from the skeleton and the deterioration of bone microarchitecture. Alkalinization through supplementation with potassium citrate (K citrate) has been pr...

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Bibliographic Details
Published in:PLoS One
Main Authors: Granchi, Donatella, Torreggiani, Elena, Massa, Annamaria, Caudarella, Renata, Di Pompo, Gemma, Baldini, Nicola
Format: Artigo
Language:Inglês
Published: Public Library of Science 2017
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513456/
https://ncbi.nlm.nih.gov/pubmed/28715463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181230
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