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A novel Alzheimer’s disease drug candidate targeting inflammation and fatty acid metabolism

BACKGROUND: CAD-31 is an Alzheimer’s disease (AD) drug candidate that was selected on the basis of its ability to stimulate the replication of human embryonic stem cell-derived neural precursor cells as well as in APPswe/PS1ΔE9 AD mice. To move CAD-31 toward the clinic, experiments were undertaken t...

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Detalhes bibliográficos
Publicado no:Alzheimers Res Ther
Main Authors: Daugherty, Daniel, Goldberg, Joshua, Fischer, Wolfgang, Dargusch, Richard, Maher, Pamela, Schubert, David
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5513091/
https://ncbi.nlm.nih.gov/pubmed/28709449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13195-017-0277-3
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