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Use of haplotypes to identify regions harbouring lethal recessive variants in pigs

BACKGROUND: Lethal recessive genetic variants are maintained at relatively low frequencies in a population in the heterozygous state, but by definition are fatal and therefore unobserved in the homozygous state. Since haplotypes allow the tagging of rare and untyped genetic variants, they have poten...

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Bibliografiset tiedot
Julkaisussa:Genet Sel Evol
Päätekijät: Howard, David M., Pong-Wong, Ricardo, Knap, Pieter W., Woolliams, John A.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: BioMed Central 2017
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512953/
https://ncbi.nlm.nih.gov/pubmed/28709397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12711-017-0332-3
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