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New approaches for characterization of the genetic stability of vaccine cell lines

The genetic stability of cell lines is a critical analytical attribute required to demonstrate the quality of cells over time. During cell passage, mutations can arise in the genomic DNA, potentially leading to changes in the final vaccine product. The identity and integrity of master cell banks, ex...

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Bibliografiska uppgifter
I publikationen:Hum Vaccin Immunother
Huvudupphovsmän: Ng, Siemon, Gisonni-Lex, Lucy, Azizi, Ali
Materialtyp: Artigo
Språk:Inglês
Publicerad: Taylor & Francis 2017
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512780/
https://ncbi.nlm.nih.gov/pubmed/28333573
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1295191
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