F199E substitution reduced toxicity of Clostridium perfringens epsilon toxin by depriving the receptor binding capability

Epsilon toxin (ETX), a potent toxin, is produced by types B and D strains of Clostridium perfringens, which could cause severe diseases in humans and domestic animals. Mutant rETX(F199E) was previously demonstrated to be a good vaccine candidate. However, the mechanism concerned remains unknown. To...

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Detalhes bibliográficos
Publicado no:Hum Vaccin Immunother
Main Authors: Kang, Jingjing, Gao, Jie, Yao, Wenwu, Kang, Lin, Gao, Shan, Yang, Hao, Ji, Bin, Li, Ping, Liu, Jing, Yao, Jiahao, Xin, Wenwen, Zhao, Baohua, Wang, Jinglin
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2017
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512772/
https://ncbi.nlm.nih.gov/pubmed/28304231
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/21645515.2017.1303022
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