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v-Ha-ras transgene abrogates the initiation step in mouse skin tumorigenesis: effects of phorbol esters and retinoic acid.

Experimental carcinogenesis has led to a concept that defines two discrete stages in the development of skin tumors: (i) initiation, which is accomplished by using a mutagen that presumably activates a protooncogene, and (ii) promotion, which is a reversible process brought about most commonly by re...

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Bibliografiska uppgifter
I publikationen:Proc Natl Acad Sci U S A
Huvudupphov: Leder, A, Kuo, A, Cardiff, R D, Sinn, E, Leder, P
Materialtyp: Artigo
Språk:Inglês
Utgiven: National Academy of Sciences 1990
Ämnen:
Länkar:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55127/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2251261/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.23.9178
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