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A Salmonella nanoparticle mimic overcomes multidrug resistance in tumours
Salmonella enterica serotype Typhimurium is a food-borne pathogen that also selectively grows in tumours and functionally decreases P-glycoprotein (P-gp), a multidrug resistance transporter. Here we report that the Salmonella type III secretion effector, SipA, is responsible for P-gp modulation thro...
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Publicado no: | Nat Commun |
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Main Authors: | , , , , , , , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Nature Publishing Group
2016
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5512628/ https://ncbi.nlm.nih.gov/pubmed/27452236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms12225 |
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