Microfluidic single-cell transcriptional analysis rationally identifies novel surface marker profiles to enhance cell-based therapies

Current progenitor cell therapies have only modest efficacy, which has limited their clinical adoption. This may be the result of a cellular heterogeneity that decreases the number of functional progenitors delivered to diseased tissue, and prevents correction of underlying pathologic cell populatio...

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Veröffentlicht in:Nat Commun
Hauptverfasser: Rennert, Robert C., Januszyk, Michael, Sorkin, Michael, Rodrigues, Melanie, Maan, Zeshaan N., Duscher, Dominik, Whittam, Alexander J., Kosaraju, Revanth, Chung, Michael T., Paik, Kevin, Li, Alexander Y., Findlay, Michael, Glotzbach, Jason P., Butte, Atul J., Gurtner, Geoffrey C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group 2016
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512622/
https://ncbi.nlm.nih.gov/pubmed/27324848
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms11945
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