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In vitro assembly of infectious nucleocapsids of bacteriophage phi 6: formation of a recombinant double-stranded RNA virus.

A system is described for assembling infectious bacteriophage phi 6 nucleocapsids in vitro. Procapsids encoded by cDNA copies of genomic segment L in Escherichia coli were used to package and replicate viral RNA segments. The resulting filled particles were shown to be capable of infecting host cell...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Olkkonen, V M, Gottlieb, P, Strassman, J, Qiao, X Y, Bamford, D H, Mindich, L
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1990
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55126/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2251260/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.23.9173
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