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A macrocyclic peptide ligand binds the oncogenic microRNA-21 precursor and suppresses Dicer processing
MicroRNAs (miRNAs) help orchestrate cellular growth and survival through post-transcriptional mechanisms. The dysregulation of miRNA biogenesis can lead to cellular growth defects, chemotherapeutic resistance and plays a direct role in the development of many chronic diseases. Among these RNAs, miR-...
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| Publicado no: | ACS Chem Biol |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5512579/ https://ncbi.nlm.nih.gov/pubmed/28437065 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschembio.7b00180 |
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