Obesity-Induced Diabetes and Lower Urinary Tract Fibrosis Promote Urinary Voiding Dysfunction in a Mouse Model

BACKGROUND: Progressive aging- and inflammation-associated fibrosis effectively remodels the extracellular matrix (ECM) to increase prostate tissue stiffness and reduce urethral flexibility, resulting in urinary flow obstruction and lower urinary tract symptoms (LUTS). In the current study, we sough...

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Publicado en:Prostate
Autores principales: Gharaee-Kermani, Mehrnaz, Rodriguez-Nieves, Jose A., Mehra, Rohit, Vezina, Chad A., Sarma, Aruna V., Macoska, Jill A.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2013
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512573/
https://ncbi.nlm.nih.gov/pubmed/23532836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pros.22662
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