TGR5 contributes to glucoregulatory improvements after vertical sleeve gastrectomy in mice

OBJECTIVE: Vertical sleeve gastrectomy (VSG) produces high rates of type 2 diabetes remission; however, the mechanisms responsible remain incompletely defined. VSG increases circulating bile acid concentrations and bile acid signalling through TGR5 improves glucose homeostasis. Therefore, we investi...

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Bibliografski detalji
Izdano u:Gut
Glavni autori: McGavigan, Anne K, Garibay, Darline, Henseler, Zachariah M, Chen, Jack, Bettaieb, Ahmed, Haj, Fawaz G, Ley, Ruth E, Chouinard, Michael L, Cummings, Bethany P
Format: Artigo
Jezik:Inglês
Izdano: 2015
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Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512436/
https://ncbi.nlm.nih.gov/pubmed/26511794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2015-309871
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