Surrogate Endpoints in Second-Line Trials of Targeted Agents in Metastatic Colorectal Cancer: A Literature-Based Systematic Review and Meta-Analysis

PURPOSE: The purpose of this study was to evaluate progression-free survival (PFS) and objective response rate (ORR) as surrogate endpoints of overall survival (OS) in modern clinical trials investigating the efficacy of targeted agents in the second-line treatment of metastatic colorectal cancer (m...

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Salvato in:
Dettagli Bibliografici
Pubblicato in:Cancer Res Treat
Autori principali: Cremolini, Chiara, Antoniotti, Carlotta, Pietrantonio, Filippo, Berenato, Rosa, Tampellini, Marco, Baratelli, Chiara, Salvatore, Lisa, Marmorino, Federica, Borelli, Beatrice, Nichetti, Federico, Bironzo, Paolo, Sonetto, Cristina, Bartolomeo, Maria Di, de Braud, Filippo, Loupakis, Fotios, Falcone, Alfredo, Maio, Massimo Di
Natura: Artigo
Lingua:Inglês
Pubblicazione: Korean Cancer Association 2017
Soggetti:
Meta-Analysis
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512363/
https://ncbi.nlm.nih.gov/pubmed/27857020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4143/crt.2016.249
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