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The C Terminus of the Herpes Simplex Virus UL25 Protein Is Required for Release of Viral Genomes from Capsids Bound to Nuclear Pores

The herpes simplex virus (HSV) capsid is released into the cytoplasm after fusion of viral and host membranes, whereupon dynein-dependent trafficking along microtubules targets it to the nuclear envelope. Binding of the capsid to the nuclear pore complex (NPC) is mediated by the capsid protein pUL25...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Huffman, Jamie B., Daniel, Gina R., Falck-Pedersen, Erik, Huet, Alexis, Smith, Greg A., Conway, James F., Homa, Fred L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512264/
https://ncbi.nlm.nih.gov/pubmed/28490590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00641-17
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