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Deletion of the Vaccinia Virus I2 Protein Interrupts Virion Morphogenesis, Leading to Retention of the Scaffold Protein and Mislocalization of Membrane-Associated Entry Proteins

The I2L open reading frame of vaccinia virus (VACV) encodes a conserved 72-amino-acid protein with a putative C-terminal transmembrane domain. Previous studies with a tetracycline-inducible mutant demonstrated that I2-deficient virions are defective in cell entry. The purpose of the present study wa...

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Bibliografski detalji
Izdano u:J Virol
Glavni autori: Hyun, Seong-In, Weisberg, Andrea, Moss, Bernard
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2017
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512257/
https://ncbi.nlm.nih.gov/pubmed/28490596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00558-17
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