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CFTR in a lipid raft-TNFR1 complex modulates gap junctional intercellular communication and IL-8 secretion

Mutations in the cystic fibrosis transmembrane conductance regulator (CFTR) cause a chronic inflammatory response in the lung of patients with Cystic Fibrosis (CF). We have showed that TNF-α signaling through the Src family tyrosine kinases (SFKs) was defective as determined by an inability of TNF-α...

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Detalhes bibliográficos
Publicado no:Biochim Biophys Acta
Main Authors: Dudez, Tecla, Borot, Florence, Huang, Song, Kwak, Brenda R., Bacchetta, Marc, Ollero, Mario, Stanton, Bruce A., Chanson, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512004/
https://ncbi.nlm.nih.gov/pubmed/18255040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamcr.2008.01.007
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