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A retroviral promoter is sufficient to convert proto-src to a transforming gene that is distinct from the src gene of Rous sarcoma virus.

The src genes of four natural isolates of avian sarcoma viruses differ from cellular proto-src in two genetic substitutions: the promoter of the cellular gene is replaced by a retroviral counterpart, and at least six codons from the 3' terminus are replaced by retroviral or heterologous cell-derived...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Principais autores: Zhou, H, Duesberg, P H
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 1990
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55117/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2174554/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.87.23.9128
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