Anti-fibrotic Effects of Synthetic Oligodeoxynucleotide for TGF-β1 and Smad in an Animal Model of Liver Cirrhosis

Liver fibrosis is characterized by changes in tissue architecture and extracellular matrix composition. Liver fibrosis affects not only hepatocytes but also the non-parenchymal cells such as hepatic stellate cells (HSCs), which are essential for maintaining an intact liver structure and function. Tr...

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Detalhes bibliográficos
Publicado no:Mol Ther Nucleic Acids
Main Authors: Kim, Jung-Yeon, An, Hyun-Jin, Kim, Woon-Hae, Gwon, Mi-Gyeong, Gu, Hyemin, Park, Yoon-Yub, Park, Kwan-Kyu
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2017
Assuntos:
Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511593/
https://ncbi.nlm.nih.gov/pubmed/28918026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.06.022
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