Anti-fibrotic Effects of Synthetic Oligodeoxynucleotide for TGF-β1 and Smad in an Animal Model of Liver Cirrhosis

Liver fibrosis is characterized by changes in tissue architecture and extracellular matrix composition. Liver fibrosis affects not only hepatocytes but also the non-parenchymal cells such as hepatic stellate cells (HSCs), which are essential for maintaining an intact liver structure and function. Tr...

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Publicado en:Mol Ther Nucleic Acids
Autores principales: Kim, Jung-Yeon, An, Hyun-Jin, Kim, Woon-Hae, Gwon, Mi-Gyeong, Gu, Hyemin, Park, Yoon-Yub, Park, Kwan-Kyu
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society of Gene & Cell Therapy 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511593/
https://ncbi.nlm.nih.gov/pubmed/28918026
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2017.06.022
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