Autologous Heat Shock Protein Peptide Vaccination for Newly Diagnosed Glioblastoma: Impact of Peripheral PD-L1 Expression on Response to Therapy

PURPOSE: Standard therapy for newly diagnosed glioblastoma (GBM) is surgical resection, followed by concurrent radiotherapy and temozolomide chemotherapy. In this phase 2 clinical trial, the addition of an autologous heat shock protein vaccine to standard therapy was evaluated. Tumor-induced immunos...

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發表在:Clin Cancer Res
Main Authors: Bloch, Orin, Lim, Michael, Sughrue, Michael E., Komotar, Ricardo J., Abrahams, John M., O’Rourke, Donald M., D’Ambrosio, Anthony, Bruce, Jeffrey N., Parsa, Andrew T.
格式: Artigo
語言:Inglês
出版: 2017
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511566/
https://ncbi.nlm.nih.gov/pubmed/28193626
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-16-1369
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