Combination therapy for tuberculosis treatment: pulmonary administration of ethionamide and booster co-loaded nanoparticles

Tuberculosis (TB) is a leading infectious cause of death worldwide. The use of ethionamide (ETH), a main second line anti-TB drug, is hampered by its severe side effects. Recently discovered “booster” molecules strongly increase the ETH efficacy, opening new perspectives to improve the current clini...

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Pubblicato in:Sci Rep
Autori principali: Costa-Gouveia, Joana, Pancani, Elisabetta, Jouny, Samuel, Machelart, Arnaud, Delorme, Vincent, Salzano, Giuseppina, Iantomasi, Raffaella, Piveteau, Catherine, Queval, Christophe J., Song, Ok-Ryul, Flipo, Marion, Deprez, Benoit, Saint-André, Jean-Paul, Hureaux, José, Majlessi, Laleh, Willand, Nicolas, Baulard, Alain, Brodin, Priscille, Gref, Ruxandra
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511234/
https://ncbi.nlm.nih.gov/pubmed/28710351
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05453-3
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