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The essential role of TAp73 in bortezomib-induced apoptosis in p53-deficient colorectal cancer cells

Mutations in the tumor suppressor p53 are among the most highly occurring events in colorectal cancer (CRC). Such mutations have been shown to influence the sensitivity of cancer cells to chemotherapeutic agents. However their impact on the efficacy of the proteasomal inhibitor bortezomib remains co...

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Dades bibliogràfiques
Publicat a:Sci Rep
Autors principals: Dabiri, Yasamin, Kalman, Sara, Gürth, Clara-Marie, Kim, Jee Young, Mayer, Viola, Cheng, Xinlai
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511205/
https://ncbi.nlm.nih.gov/pubmed/28710427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05813-z
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