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The essential role of TAp73 in bortezomib-induced apoptosis in p53-deficient colorectal cancer cells

Mutations in the tumor suppressor p53 are among the most highly occurring events in colorectal cancer (CRC). Such mutations have been shown to influence the sensitivity of cancer cells to chemotherapeutic agents. However their impact on the efficacy of the proteasomal inhibitor bortezomib remains co...

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Podrobná bibliografie
Vydáno v:Sci Rep
Hlavní autoři: Dabiri, Yasamin, Kalman, Sara, Gürth, Clara-Marie, Kim, Jee Young, Mayer, Viola, Cheng, Xinlai
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511205/
https://ncbi.nlm.nih.gov/pubmed/28710427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05813-z
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