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The essential role of TAp73 in bortezomib-induced apoptosis in p53-deficient colorectal cancer cells
Mutations in the tumor suppressor p53 are among the most highly occurring events in colorectal cancer (CRC). Such mutations have been shown to influence the sensitivity of cancer cells to chemotherapeutic agents. However their impact on the efficacy of the proteasomal inhibitor bortezomib remains co...
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| Veröffentlicht in: | Sci Rep |
|---|---|
| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
Nature Publishing Group UK
2017
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5511205/ https://ncbi.nlm.nih.gov/pubmed/28710427 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05813-z |
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