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Prophylactic tributyrin treatment mitigates chronic-binge alcohol-induced intestinal barrier and liver injury

BACKGROUND/AIM: Impaired gut-liver axis is a potential factor contributing to alcoholic liver disease. Ethanol depletes intestinal integrity and causes gut dysbiosis. Butyrate, a fermentation byproduct of gut microbiota, is altered negatively following chronic ethanol exposure. This study aimed to d...

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Bibliografiske detaljer
Udgivet i:J Gastroenterol Hepatol
Main Authors: Cresci, Gail A., Glueck, Bryan, McMullen, Megan R., Xin, Wei, Allende, Danielle, Nagy, Laura E.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511097/
https://ncbi.nlm.nih.gov/pubmed/28087985
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jgh.13731
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