Effect of nascent peptide steric bulk on elongation kinetics in the ribosome exit tunnel

All proteins are synthesized by the ribosome, a macromolecular complex that accomplishes the life-sustaining tasks of faithfully decoding mRNA and catalyzing peptide bond formation at the peptidyl transferase center (PTC). The ribosome has evolved an exit tunnel to host the elongating new peptide, p...

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Gepubliceerd in:J Mol Biol
Hoofdauteurs: Po, Pengse, Delaney, Erin, Gamper, Howard, Szanti-Kis, Miklos, Speight, Lee, Tu, LiWei, Kosolapov, Andrey, Petersson, E. James, Hou, Ya-Ming, Deutsch, Carol
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2017
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5511029/
https://ncbi.nlm.nih.gov/pubmed/28483649
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2017.04.019
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