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A novel twelve class fluctuation test reveals higher than expected mutation rates for influenza A viruses
Influenza virus’ low replicative fidelity contributes to its capacity for rapid evolution. Clonal sequencing and fluctuation tests have suggested that the influenza virus mutation rate is 2.7 × 10(–6) - 3.0 × 10(–5) substitutions per nucleotide per strand copied (s/n/r). However, sequencing assays a...
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| Udgivet i: | eLife |
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| Main Authors: | , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
eLife Sciences Publications, Ltd
2017
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5511008/ https://ncbi.nlm.nih.gov/pubmed/28598328 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.26437 |
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