Vaccination with a live attenuated Acinetobacter baumannii deficient in thioredoxin provides protection against systemic Acinetobacter infection

Multi-drug resistant Acinetobacter baumannii (MDR-Ab), an opportunistic pathogen associated with nosocomial and combat related infections, has a high mortality due to its virulence and limited treatment options. Deletion of the thioredoxin gene (trxA) from a clinical isolate of MDR-Ab resulted in a...

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Udgivet i:Vaccine
Main Authors: Ainsworth, Sarah, Ketter, Patrick M., Yu, Jieh-Juen, Grimm, Rose C., May, Holly C., Cap, Andrew P., Chambers, James P., Guentzel, M. Neal, Arulanandam, Bernard P.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510955/
https://ncbi.nlm.nih.gov/pubmed/28522011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2017.05.017
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