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Inhibition of protein synthesis in intact HeLa cells by Shigella dysenteriae 1 toxin.

Shiga toxin purified to near homogeneity from cell lysates of Shigella dysenteriae 1 inhibited protein and deoxyribonucle acid syntheses in intact HeLa cells. Inhibition was dependent on toxin concentration and time of incubation. A minimal latent period of 30 min was observed with saturating doses...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Brown, J E, Rothman, S W, Doctor, B P
Format: Artigo
Sprache:Inglês
Veröffentlicht: 1980
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC551080/
https://ncbi.nlm.nih.gov/pubmed/6156915
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