Arthritis-inducing ability of a synthetic adjuvant, N-acetylmuramyl peptides, and bacterial disaccharide peptides related to different oil vehicles and their composition.

A synthetic adjuvant, N-acetylmuramyl-L-alanyl-D-isoglutamine (MDP), failed to produce polyarthritis with a wide dose range in a water-in-oil emulsion of mineral oil such as liquid paraffin, Drakeol, or heavy mineral oil. MDP, however, produced moderate to severe arthritis with almost 100% incidence...

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Detalhes bibliográficos
Main Authors: Kohashi, O, Tanaka, A, Kotani, S, Shiba, T, Kusumoto, S, Yokogawa, K, Kawata, S, Ozawa, A
Formato: Artigo
Idioma:Inglês
Publicado em: 1980
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC551076/
https://ncbi.nlm.nih.gov/pubmed/7399708
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