Lack of Antiparkinsonian Effects of Systemic Injections of the Specific T-type Calcium Channel Blocker ML218 in MPTP-Treated Monkeys

Dopaminergic medications ameliorate many of the motor impairments of Parkinson’s disease (PD). However, parkinsonism is often only partially reversed by these drugs, and they can have significant side effects. Therefore, a need remains for novel treatments of parkinsonism. Studies in rodents and pre...

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Pubblicato in:ACS Chem Neurosci
Autori principali: Galvan, Adriana, Devergnas, Annaelle, Pittard, Damien, Masilamoni, Gunasingh, Vuong, Jocelyn, Daniels, J. Scott, Lindsley, Craig W., Morrison, Ryan D., Wichmann, Thomas
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5510653/
https://ncbi.nlm.nih.gov/pubmed/27596273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acschemneuro.6b00186
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