Metabotropic glutamate receptor 5 antagonist protects dopaminergic and noradrenergic neurons from degeneration in MPTP-treated monkeys

Degeneration of the dopaminergic nigrostriatal system and of noradrenergic neurons in the locus coeruleus are important pathological features of Parkinson’s disease. There is an urgent need to develop therapies that slow down the progression of neurodegeneration in Parkinson’s disease. In the presen...

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Autors principals: Masilamoni, Gunasingh J., Bogenpohl, James W., Alagille, David, Delevich, Kristen, Tamagnan, Gilles, Votaw, John R., Wichmann, Thomas, Smith, Yoland
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2011
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Original Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3122374/
https://ncbi.nlm.nih.gov/pubmed/21705423
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/brain/awr137
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