An autocrine ATP release mechanism regulates basal ciliary activity in airway epithelium

KEY POINTS: Extracellular ATP, in association with [Ca(2+)](i) regulation, is required to maintain basal ciliary beat frequency. Increasing extracellular ATP levels increases ciliary beating in airway epithelial cells, maintaining a sustained response by inducing the release of additional ATP. Extra...

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Veröffentlicht in:J Physiol
Hauptverfasser: Droguett, Karla, Rios, Mariana, Carreño, Daniela V., Navarrete, Camilo, Fuentes, Christian, Villalón, Manuel, Barrera, Nelson P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2017
Schlagworte:
Respiratory
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509870/
https://ncbi.nlm.nih.gov/pubmed/28422293
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP273996
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