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An increased extrasynaptic NMDA tone inhibits A‐type K(+) current and increases excitability of hypothalamic neurosecretory neurons in hypertensive rats

KEY POINTS: A functional coupling between extrasynaptic NMDA receptors (eNMDARs) and the A‐type K(+) current (I (A)) influences homeostatic firing responses of magnocellular neurosecretory cells (MNCs) to a physiological challenge. However, whether an altered eNMDAR–I (A) coupling also contributes t...

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Pubblicato in:J Physiol
Autori principali: Zhang, Meng, Biancardi, Vinicia C., Stern, Javier E.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509869/
https://ncbi.nlm.nih.gov/pubmed/28378360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP274327
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