Autoimmune Regulator Deficiency Results in a Decrease in STAT1 Levels in Human Monocytes

Autoimmune polyendocrinopathy-candidiasis-ectodermal dystrophy (APECED) is a rare primary immunodeficiency disorder typically caused by biallelic autoimmune regulator (AIRE) mutations that manifests with chronic mucocutaneous candidiasis (CMC) and autoimmunity. Patients with STAT1 gain-of-function (...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Front Immunol
Prif Awduron: Zimmerman, Ofer, Rosen, Lindsey B., Swamydas, Muthulekha, Ferre, Elise M. N., Natarajan, Mukil, van de Veerdonk, Frank, Holland, Steven M., Lionakis, Michail S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Frontiers Media S.A. 2017
Pynciau:
Immunology
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509791/
https://ncbi.nlm.nih.gov/pubmed/28769929
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2017.00820
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