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Inhibition of the CRF(1) receptor influences the activity of antidepressant drugs in the forced swim test in rats
Hyperactivity of the hypothalamic-pituitary-adrenal axis (HPA) and impairment of the central corticotropin-releasing factor (CRF) system are factors in the pathogenesis of depression. Though several antagonists of the CRF(1) receptor were effective in the recognized behavioral tests for antidepressa...
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| Publicado no: | Naunyn Schmiedebergs Arch Pharmacol |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Berlin Heidelberg
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5509780/ https://ncbi.nlm.nih.gov/pubmed/28429110 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00210-017-1377-0 |
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