Lack of the Nlrp3 Inflammasome Improves Mice Recovery Following Traumatic Brain Injury

Treatment for traumatic brain injury (TBI) remains elusive despite compelling evidence from animal models for a variety of therapeutic targets. The activation of the NLRP3 (Nucleotide-binding oligomerization domain-like receptor family pyrin domain-containing 3) inflammasome has been proposed as key...

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Vydáno v:Front Pharmacol
Hlavní autoři: Irrera, Natasha, Pizzino, Gabriele, Calò, Margherita, Pallio, Giovanni, Mannino, Federica, Famà, Fausto, Arcoraci, Vincenzo, Fodale, Vincenzo, David, Antonio, Francesca, Cosentino, Minutoli, Letteria, Mazzon, Emanuela, Bramanti, Placido, Squadrito, Francesco, Altavilla, Domenica, Bitto, Alessandra
Médium: Artigo
Jazyk:Inglês
Vydáno: Frontiers Media S.A. 2017
Témata:
Pharmacology
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509758/
https://ncbi.nlm.nih.gov/pubmed/28769794
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2017.00459
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