Polydextrose changes the gut microbiome and attenuates fasting triglyceride and cholesterol levels in Western diet fed mice

Obesity and dyslipidemia are hallmarks of metabolic and cardiovascular diseases. Polydextrose (PDX), a soluble fiber has lipid lowering effects. We hypothesize that PDX reduces triglycerides and cholesterol by influencing gut microbiota, which in turn modulate intestinal gene expression. C57BL/6 mal...

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Publicat a:Sci Rep
Autors principals: Raza, Ghulam Shere, Putaala, Heli, Hibberd, Ashley A., Alhoniemi, Esa, Tiihonen, Kirsti, Mäkelä, Kari Antero, Herzig, Karl-Heinz
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2017
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509720/
https://ncbi.nlm.nih.gov/pubmed/28706193
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-05259-3
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