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A Haystack Heuristic for Autoimmune Disease Biomarker Discovery Using Next-Gen Immune Repertoire Sequencing Data

Large-scale DNA sequencing of immunological repertoires offers an opportunity for the discovery of novel biomarkers for autoimmune disease. Available bioinformatics techniques however, are not adequately suited for elucidating possible biomarker candidates from within large immunosequencing datasets...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Apeltsin, Leonard, Wang, Shengzhi, von Büdingen, H.-Christian, Sirota, Marina
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509648/
https://ncbi.nlm.nih.gov/pubmed/28706301
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04439-5
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