ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing

Spatial organization of the genome plays a central role in gene expression, DNA replication, and repair. But current epigenomic approaches largely map DNA regulatory elements outside of the native context of the nucleus. here we report assay of transposase-accessible chromatin with visualization (AT...

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Publié dans:Nat Methods
Auteurs principaux: Chen, Xingqi, Shen, Ying, Draper, Will, Buenrostro, Jason D, Litzenburger, Ulrike, Cho, Seung Woo, Satpathy, Ansuman T, Carter, Ava C, Ghosh, Rajarshi P, East-Seletsky, Alexandra, Doudna, Jennifer A, Greenleaf, William J, Liphardt, Jan T, Chang, Howard Y
Format: Artigo
Langue:Inglês
Publié: 2016
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509561/
https://ncbi.nlm.nih.gov/pubmed/27749837
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.4031
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