Chi-miR-4110 promotes granulosa cell apoptosis by targeting Sma- and Mad-related protein 2 (Smad2) in the caprine ovary

Follicular atresia mainly results from the apoptosis of granulosa cells (GCs). Whilst our previous investigations examined the role of chi-miR-4110 in regulating ovarian function, the present study detected the role of chi-miR-4110 in GC development. We transfected caprine GCs cultured in vitro with...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: An, Xiaopeng, Song, Yuxuan, Hou, Jinxing, Zhang, Yue, Chen, Kaiwen, Ma, Haidong, Zhao, Xinyan, Li, Guang, Gao, Kexin, Wang, Shan, Cao, Binyun, Bai, Yueyu
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509297/
https://ncbi.nlm.nih.gov/pubmed/28704526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0181162
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