IL-13 is a central mediator of chemical-induced airway hyperreactivity in mice

BACKGROUND: While the importance of the Th2 cytokine IL-13 as a central mediator of airway hyperreactivity (AHR) has been described in allergic protein-induced asthma, this has never been investigated in chemical-induced asthma. OBJECTIVE: We examined the importance of IL-13 in a mouse model of chem...

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Udgivet i:PLoS One
Main Authors: Devos, Fien C., Pollaris, Lore, Cremer, Jonathan, Seys, Sven, Hoshino, Tomoaki, Ceuppens, Jan, Talavera, Karel, Nemery, Benoit, Hoet, Peter H. M., Vanoirbeek, Jeroen A. J.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509233/
https://ncbi.nlm.nih.gov/pubmed/28704401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0180690
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