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Age-dependent Functional Crosstalk Between Cardiac Fibroblasts and Cardiomyocytes in a 3D Engineered Cardiac Tissue

Complex heterocellular interactions between cardiomyocytes and fibroblasts in the heart involve their bidirectional signaling via cell-cell contacts, paracrine factors, and extracellular matrix (ECM). These interactions vary with heart development and pathology leading to changes in cardiac structur...

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Bibliographic Details
Published in:Acta Biomater
Main Authors: Li, Yanzhen, Asfour, Huda, Bursac, Nenad
Format: Artigo
Language:Inglês
Published: 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5509073/
https://ncbi.nlm.nih.gov/pubmed/28455218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.actbio.2017.04.027
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